OMD (Osteomodulin) is a Protein Coding gene. Diseases associated with OMD include Bladder Carcinoma In Situ and Anthracosilicosis . Among its related pathways are Diseases of glycosylation and HIV Life Cycle . An important paralog of this gene is KERA.

Osteoadherin (OSAD) is a bone proteoglycan containing keratan sulfate that belongs to the small leucine-rich proteoglycan (SLRP) family. Osteoadherin promotes Integrin αvβ3-mediated cell binding. The central region of Osteoadherin consists of eleven B-type, leucine-rich repeats ranging in length from 20 to 30 residues.

1998-07-03 · Osteoadherin, a Cell-binding Keratan Sulfate Proteoglycan in Bone, Belongs to the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix. *. Osteoadherin is a recently described bone proteoglycan containing keratan sulfate. It promotes integrin (α v β 3 )-mediated cell binding (Wendel, M., Sommarin, Y., and Heinegård, D. (1998) J. Cell Osteoadherin (OSAD), a keratan sulphate PG is a member of the small leucine-rich (SLRP) family of PGs and unlike other SLRPs, OSAD expression is restricted to mineralized tissues. It is proposed to have a high affinity for hydroxyapatite and has been shown to be expressed by mature osteoblasts but its exact role remains to be elucidated. Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP). Leucine-rich repeat (LRR) motifs consist of approximately 20 - 30 amino acids (aa) with conserved leucine spacing, folded into a structure with one beta-sheet and one alpha-helix.

Osteoadherin

The human protein, encoded by the gene OMD, is 421 amino acid residues long and has a mass of 49,492 daltons. It is a member of the Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily. This protein is reported to have a secreted cellular Anti-OMD antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody; Synonym: SLRR2C, osteoadherin; find Sigma-Aldrich-HPA069948 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.

A: Chelating agents such as EDTA, Heparin and Citrate can bind metal ions from the functional domain of Osteoadherin causing degradation of its protein structure. Osteoadherin may be denatured as a result and may compromise the assay's measurements.

141, 839–847). The primary structure of bovine osteoadherin has now been determined by nucleotide sequencing of a cDNA clone from a primary bovine osteoblast expression library. The entire Osteoadherin HDR Plasmid (h) is recommended for co-transfection with Osteoadherin CRISPR/Cas9 KO Plasmid (h) Osteoadherin HDR Plasmid (h) consists of a pool of 2-3 plasmids, each containing a homology-directed DNA repair (HDR) template corresponding to the cut sites generated by the Osteoadherin CRISPR/Cas9 KO Plasmid (h) Anti-OMD antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody; Synonym: SLRR2C, osteoadherin; find Sigma-Aldrich-HPA069948 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.

For osteoadherin (also called osteomodulin), a cluster of sulfotyrosines is found in the N-terminal region, while two adjacent sulfotyrosine residues are present in the C-terminal region. Likewise, for the remaining class II and III SLRPs, sulfotyrosines have been predicted in the N-terminal regions.

uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs. Osteoadherin is Jul 3, 1998 Osteoadherin is a recently described bone proteoglycan containing keratan sulfate. It promotes integrin (alphav beta3)-mediated cell binding Homo sapiens.

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1998-07-03 · Osteoadherin, a Cell-binding Keratan Sulfate Proteoglycan in Bone, Belongs to the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix. *.

An important paralog of this gene is KERA. T1 - Ultrastructural distribution of osteoadherin in rat bone shows a pattern similar to that of bone sialoprotein.
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Osteomodulin (OMD), also called osteoadherin, belongs to the family of leucine- rich repeat proteins (SLRPs) of the extracellular matrix, which have crucial roles

The primary structure of bovine osteoadherin has now been determined by nucleo … 2019-10-18 · Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs. Osteoadherin is highly expressed in mineralized tissues, including bone and dentin; however, it's precise roles remain unknown. 1998-07-03 · Osteoadherin, a Cell-binding Keratan Sulfate Proteoglycan in Bone, Belongs to the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix.

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Osteoadherin is a recently described bone proteoglycan containing keratan sulfate. It promotes integrin (alphav beta3)-mediated cell binding (Wendel, M., Sommarin, Y., and Heinegârd, D. (1998) J. Cell Biol. 141, 839-847). The primary structure of bovine osteoadherin has now been determined by nucleo …

This subsection of the Names and Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs.

Anti-OMD antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody; Synonym: SLRR2C, osteoadherin; find Sigma-Aldrich-HPA069948 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.

Quantitate human OMD in supernatant, serum and plasma. Sensitivity: 1.4 ng/mL Osteoadherin (OSAD) is a keratan sulfate proteoglycan recently isolated from bovine and rat bone. Based on results obtained from in vitro experiments, the protein was shown to bind osteoblasts via the integrin receptor alpha(v)beta(3).

Osteoadherin may be denatured as a result and may compromise the assay's measurements. Our Osteoadherin/OSAD/OMD Antibodies can be used in a variety of model species: Human, Mouse. Use the list below to choose the Osteoadherin/OSAD/OMD Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and … 1998-05-01 There are currently no images for Osteoadherin/OSAD/OMD Antibody (NBP2-89674). Every product we sell is backed by Novus' 100% Guarantee.If you have used this product, please submit your images and reviews to earn reward points. Osteoadherin is highly expressed in mineralized tissues, including bone and dentin; however, it's precise roles remain unknown.